Go Back

Loaded Meat Lover’s Pizza Casserole

A delightful casserole combining the best tastes of pizza with a meat lover's twist, perfect for gatherings or a cozy family dinner.
Print Recipe Pin Recipe
Prep Time 30 minutes
Cook Time 45 minutes
Total Time 1 hour 15 minutes
Course Dinner, Main Course
Cuisine American, Italian
Servings 8 servings
Calories 450 kcal

Ingredients
  

For the Meat

  • 1 lb ground beef Consider substituting with ground turkey for a leaner option.
  • 1 lb Italian sausage Adds a spicy dimension; feel free to use chicken sausage.
  • 12 oz pepperoni slices A must for pizza flavor; try turkey pepperoni for a healthier alternative.

For the Vegetables

  • 1 large onion, chopped Enhances aroma; shallots work well for milder flavor.
  • 3 cloves garlic, minced For a flavor punch; garlic powder can be a quick substitute.

For the Sauce and Pasta

  • 2 cups marinara sauce Homemade is best; consider a low-sodium variety.
  • 4 cups cooked pasta (penne or rotini) You can use gluten-free pasta or zucchini noodles for a low-carb option.

For the Cheese

  • 2 cups mozzarella cheese, shredded Essential for cheesy goodness; swap for part-skim mozzarella.
  • 1 cup Parmesan cheese, grated Adds a nutty flavor; nutritional yeast is a vegan substitute.

For Seasoning

  • 1 tsp Italian seasoning Feel free to mix your own with dried basil, oregano, and thyme.
  • to taste Salt and pepper A pinch of red pepper flakes can kick up the heat.

Instructions
 

Preparation

  • Preheat your oven to 350°F (175°C). In a large skillet over medium heat, brown the ground beef and Italian sausage. Once cooked, drain any excess fat.
  • Add the chopped onion and minced garlic to the skillet, cooking until the onion is translucent (about 5 minutes).
  • Stir in the marinara sauce, cooked pasta, Italian seasoning, salt, and pepper. Mix everything evenly.

Assembly

  • In a greased 9x13-inch baking dish, layer half of the pasta mixture, then half of the mozzarella and Parmesan cheeses. Repeat to create a second layer.

Baking

  • Cover the dish with aluminum foil and bake for 25 minutes. Remove the foil and add the pepperoni on top. Bake uncovered for an additional 20 minutes until the cheese is bubbly and golden.

Cooling and Serving

  • Let the casserole cool for about 10 minutes before serving.

Notes

Serve with a side salad dressed in light vinaigrette or garlic bread. For extra heat, offer crushed red pepper flakes or chili oil.
Keyword Casserole, Comfort Food, Loaded Meat Lover’s Pizza Casserole, Meat Lovers, Pizza